Eslicarbazepine Acetate( BIA 2-093 )

Catalog No. M13678 CAS No. 236395-14-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Eslicarbazepine Acetate
Note

Research use only, not for human use.
Brief Description

Eslicarbazepine acetate is an antiepileptic drug.
Description

Eslicarbazepine acetate is an antiepileptic drug. (In Vivo):Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.
In Vitro

——
In Vivo

Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.
Synonyms

BIA 2-093
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Neurological Disease
Indication

——

CAS Number

236395-14-5
Formula Weight

296.324
Molecular Formula

C17H16N2O3
Purity

>98% (HPLC)
Solubility

DMSO: 59 mg/mL (199.1 mM)/Ethanol: 11 mg/mL (37.12 mM)
SMILES

O=C(N1C2=CC=CC=C2C[C@H](OC(C)=O)C3=CC=CC=C31)N
Chemical Name

(S)-10-Acetoxy- 10,11-dihydro- 5H-dibenz[b,f]azepine- 5-carboxamide

1.Sierra-Paredes G, et al. BMC Neurosci. 2014, 15:134.

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